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learn acetyl methionine
learn ACETYL TETRAPEPTIDE-2
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5 / 954 resultsresearch Acetyl-CoA Synthesis in the Skin Is a Key Determinant of Systemic Lipid Homeostasis
This study investigates the role of ATP-citrate lyase (ACLY) in lipid metabolism by using inducible whole-body Acly-knockout mice. The findings reveal that ACLY is essential for skin homeostasis, as its deficiency leads to upregulation of acetyl-CoA synthetase ACSS2. When both Acly and Acss2 are deleted from the skin, it results in significant skin abnormalities, affecting lipid production in the epidermis and sebaceous glands differently. The epidermis experiences a depletion of barrier lipids, while sebaceous glands increase sebum production, partly due to circulating fatty acids and adipose lipolysis. Dietary fat supplementation enhances sebum production and partially mitigates lipoatrophy and skin abnormalities. The study underscores the importance of cytosolic acetyl-CoA synthesis in skin barrier integrity and positions the skin as a crucial organ in systemic lipid regulation.
research The Vitamin B5/Coenzyme A Axis: A Target for Immunomodulation?
Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.
research The Acyl-CoA Binding Protein Is Required For Normal Epidermal Barrier Function In Mice
ACBP is crucial for healthy skin in mice.
research Acyl-CoA Binding Protein and Epidermal Barrier Function
ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.
research Role of S-Palmitoylation by ZDHHC13 in Mitochondrial Function and Metabolism in Liver
ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.
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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
by
nkrata
in Research
830 upvotes
1 year ago Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Fats on your Head to Stop Hair Loss?
The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.
community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System
PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.
community What are the best hair care products for us who use minox, keto, fin, and microneedling? Share!
Hair care products for those using minox, keto, fin, and microneedling are discussed. Nizoral 2%, Revita shampoo, Nioxin system 2, Aveda thickening tonic, Hanz De Fuko Claymation, and Morrocanoil Texture Clay are mentioned as options.
community Acetyl L-Carnitine during treatment?
The user started finasteride two weeks ago and has been using minoxidil for over a month, while also supplementing with Acetyl L-Carnitine. They are curious if others have experienced hair shedding or growth with Acetyl L-Carnitine, especially when used with finasteride and minoxidil.