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Angiotensin-Converting Enzyme 2

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research The Impact of Angiotensin-Converting Enzyme 2 Expression Levels in Patients with Comorbidities on COVID-19 Severity: A Comprehensive Review

52 citations , August 2021 in “Microorganisms”

Higher ACE2 levels in certain tissues may worsen COVID-19 in people with other health issues, especially older adults.

research Role of ACE2 Polymorphism in COVID-19: Impact of Age

6 citations , May 2021 in “Clinical Chemistry and Laboratory Medicine”

Different ACE2 gene versions may affect COVID-19 impact based on age and suggest some hair loss drugs could be potential treatments.

research Analyzing the Role of ACE2, AR, MX1, and TMPRSS2 Genetic Markers for COVID-19 Severity

9 citations , June 2023 in “Human Genomics”

MX1 and AR genes are linked to milder COVID-19, while TMPRSS2 increases severe risk, especially in women.

research From Bedside to Bench: Regulation of Host Factors in SARS-CoV-2 Infection

4 citations , April 2021 in “Experimental and Molecular Medicine”

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

research COVID-19 and Sex Differences: Mechanisms and Biomarkers

185 citations , August 2020 in “Mayo Clinic Proceedings”

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

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community Adrogens and Covid-19

in Treatment 7 upvotes 5 years ago

The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.