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Different skin diseases show unique patterns of skin cell separation, cell death, and granular layer changes.

Papular acantholytic dyskeratosis of the vulva is a rare, benign skin condition that can be managed conservatively.

Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.

Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.

Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.