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GlossaryAdeno-Associated Virus (AAV)

small virus used in gene therapy for precise genetic delivery

Adeno-Associated Virus (AAV) is a small virus that infects humans but is not known to cause disease. It is commonly used in gene therapy because it can deliver genetic material into cells with high precision and low immune response.

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research Development of Gene Therapy for Inner Ear Disease: Using Bilateral Vestibular Hypofunction as a Vehicle for Translational Research

28 citations, January 2011 in “Hearing Research”

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

research CaBP1 and 2 Enable Sustained CaV1.3 Calcium Currents and Synaptic Transmission in Inner Hair Cells

January 2024

CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.

research In Vivo Reprogramming of Wound-Resident Cells Generates Skin with Hair

March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Scientists can now create skin with hair by reprogramming cells in wounds.

research Rps14 Upregulation Promotes Inner Ear Progenitor Proliferation and Hair Cell Regeneration in the Neonatal Mouse Cochlea

September 2022 in “Research Square (Research Square)”

Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.

research Basic Concepts, Current Evidence, And Future Potential For Gene Therapy In Managing Cutaneous Wounds

6 citations, June 2019 in “Biotechnology Letters”

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

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community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community If you can give one advice to your younger self then what that would be?

in Research/Science 2724 upvotes 5 months ago

Users discussed hair loss treatments, specifically minoxidil and finasteride. They shared personal experiences and advice on starting these treatments early.