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A Genomic Approach to Susceptibility and Pathogenesis Leads to Identifying Potential Novel Therapeutic Targets in Androgenetic Alopecia

research A genomic approach to susceptibility and pathogenesis leads to identifying potential novel therapeutic targets in androgenetic alopecia

13 citations , March 2017 in “Genomics”

This study reported that pathways related to apoptosis, cell proliferation, and WNT signaling might be key drivers of hair loss in androgenetic alopecia, guiding potential targets for therapy development.

research The Genetics of Seborrheic Dermatitis: A Candidate Gene Approach and Pilot Genome-Wide Association Study

15 citations , December 2017 in “Journal of Investigative Dermatology”

This study identified two genome-wide significant genetic associations with seborrheic dermatitis, suggesting a potential genetic susceptibility contributing to the disease's pathogenesis.

research Association between IL16 gene polymorphisms and susceptibility to alopecia areata in the Korean population

11 citations , December 2013 in “International Journal of Dermatology”

This study found that variations in the IL16 gene, specifically SNPs rs17875491 and rs11073001, may be associated with increased risk and phenotype expression of alopecia areata in the Korean population.

research Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss

19 citations , July 2020 in “EBioMedicine”

In this study, the researchers identified a variant in the CCHCR1 gene associated with an alopecia areata subtype characterized by impaired keratinization and autoimmune events.

research Association between EGF and EGFR Gene Polymorphisms and Susceptibility to Alopecia Areata in the Korean Population

2 citations , January 2019 in “Annals of Dermatology”

Certain gene variations in EGF and EGFR may increase the risk of alopecia areata in Koreans.

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community I [19m] have been on finastride for almost 2 years and I am still receding

in Finasteride/Dutasteride 44 upvotes 1 year ago

A 19-year-old male has been using finasteride and minoxidil for nearly two years but continues to experience hairline recession. He is considering switching to dutasteride and exploring options like hair systems and potential future hair transplants.

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Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi