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Research

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research Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society* Clinical Practice Guideline

2170 citations , September 2017 in “The Journal of Clinical Endocrinology & Metabolism”

This updated guideline from the Endocrine Society highlights the importance of endocrinologists in providing safe and effective hormone regimens for gender-affirming care, especially for adolescents who have entered puberty.

research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

1744 citations , August 2006 in “The Journal of Clinical Endocrinology and Metabolism”

This review discusses definitions of polycystic ovary syndrome and reports no new clinical results; the authors support using modified 1990 NIH criteria and acknowledge ongoing evolution as research advances.

research scMC learns biological variation through the alignment of multiple single-cell genomics datasets

822 citations , January 2021 in “Genome biology”

This study presents a new method called scMC that effectively distinguishes biological from technical variation in single-cell genomics datasets, demonstrating its ability to accurately align and detect biological signals across various experiments.

research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss

688 citations , June 2007 in “Cell Stem Cell”

This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.

research Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation

578 citations , April 1993 in “Cell”

This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.

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Community Join

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community Still losing ground after 10 months dut + minox

3 upvotes 1 month ago

The user has been using a combination of dutasteride, minoxidil, and biotin for hair loss but is experiencing a decline in hair condition after initial improvement. They are considering consulting a trichologist and switching from capsule to softgel format for better absorption.

community Indian Is The Best Place To Go Bald.😹

155 upvotes 1 month ago

Hair loss treatments like topical Minoxidil with Finasteride and Dutasteride are discussed, highlighting their low prices in India. The conversation also touches on the affordability of medications in India due to mass production and government subsidies.

community Is anyone here using lower concentrations of topical finasteride (e.g., 0.005-0.05% range) and seeing results?

in Finasteride/Dutasteride 4 upvotes 5 months ago

Users discuss the effectiveness of low-dose topical finasteride (0.005-0.05%) for hair loss, often combined with minoxidil. Some report stable results or new growth, but it's unclear if improvements are due to finasteride or minoxidil.

community [23M] Hair got better at 3 months, then much worse. What now?

in Progress Pictures 141 upvotes 8 months ago

The user experienced initial hair improvement with dutasteride and minoxidil but saw worsening at seven months, likely due to shedding. The consensus is to continue treatment, as shedding is common and improvement may take up to a year.

community Frènch Phàrmàcie gave me 10,000x the d0sage

1 year ago

A pharmacy error resulted in a finasteride solution being 100 times stronger than prescribed, not 10,000 times as initially feared. OP is advised to contact the pharmacy to clarify the preparation before traveling.

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Learn

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learn Epigallocatechin gallate-glucoside

learn Potassium Cocoyl Glycinate

learn Vascular Endothelial Growth Factor

learn Biotin

Vitamins vs. minoxidil: who wins the battle for hair growth? Minoxidil is generally more effective for hair growth than vitamins.

learn Minoxidil

Will I grow hair on my forehead? Myths and truths about minoxidil Minoxidil does not grow hair on the forehead due to low follicle density.

learn GHK-Cu

What is GHK-Cu and why is it said to be a "miracle" for hair? GHK-Cu is a copper peptide studied mainly for wound healing and skin repair; for hair loss the evidence stops at cell-culture and animal work, and no published human trial has tested it for androgenetic alopecia.

learn Aloe vera

Are random bald spots stressing you out? Aloe vera gel might be your scalp’s natural first aid. Aloe vera gel may help soothe and support scalp health for random bald spots.

learn Aminexil

How is Aminexil different from the classic minoxidil? Is one gentler? Aminexil is gentler than minoxidil and may have fewer side effects.

learn propylene glycol

learn Biotinyl-GHK

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Experts

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