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      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

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      community Self-Experiment - Topical Rapamycin or a-KB

      in Treatment  4 upvotes 4 years ago
      A user plans to create a DIY topical treatment for hair loss using Rapamycin, possibly combined with alpha-ketoglutaric acid (a-KG). They discuss the concentration and formulation process for Rapamycin, considering safety and skin penetration, and intend to apply it every other day to the scalp.

      community Can I take bicalutamide for hair loss as a man, but don’t want to transition?

      in Treatment  1 upvotes 4 days ago
      A 23-year-old man with hair loss, despite using dutasteride, oral minoxidil, and RU58841, is considering bicalutamide for regrowth but is concerned about feminization. Alternatives like topical estrogen, JXL069, and spironolactone are discussed, with suggestions to explore thyroid levels and other potential underlying conditions.

      community Oral topical minoxidil - a recipe

      in Minoxidil  2 upvotes 6 days ago
      A user in Poland created a homemade "oral topical minoxidil" using 2% topical minoxidil, propylene glycol, and vodka due to difficulty obtaining oral minoxidil. They shared a recipe and sought feedback, emphasizing caution and safety in dosing.

      community Losing my hair since 18, feel like a monster

      in Chat  36 upvotes 1 week ago
      A 21-year-old is experiencing severe hair loss despite using finasteride and minoxidil, and plans to try dutasteride. Others share similar struggles and suggest various treatments like RU58841, spironolactone, and hair systems, while emphasizing the emotional impact of hair loss.