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Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration

research Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration

72 citations , June 2001 in “Journal of Investigative Dermatology”

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

research A Review: The Location, Molecular Characterisation and Multipotency of Hair Follicle Epidermal Stem Cells

61 citations , November 2004 in “Annals of the Academy of Medicine Singapore”

Hair follicle stem cells are mainly in the bulge region and can help repair skin and form hair and glands, but more research is needed to fully understand them.

research Genetic Effects of Vascular Endothelial Growth Factor and Its Receptor 2 on Feather Maturity in Three Chicken Breeds

1 citations , January 2019 in “British Poultry Science”

VEGF and VEGFR-2 genes influence feather maturity, and specific genetic markers can improve chicken breeding.

research Characterization of Ectomesenchyme as an Origin of Epidermal Stem Cells

April 2023 in “Journal of Investigative Dermatology”

Ectomesenchyme is a key source of skin stem cells.

research A Cell Polarity Protein, aPKCλ, Is Essential for Maintaining Hair Follicle Stem Cell Quiescence and Hair Follicle Regeneration

September 2016 in “Journal of Dermatological Science”

The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.

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Community Join

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community Back from the depths - 24M, big 3

in Progress Pictures 70 upvotes 3 years ago

A 24-year-old man saw hair loss improvement after 5 months using 1 mg finasteride daily, 5% minoxidil nightly, weekly microneedling with a Dr. Pen A6 at 1.5mm, daily biotin (at least 10,000 mcg), and using a shampoo for thinning hair every other day. He experienced no side effects and confirmed his health with bloodwork.

community NW3 > NW1: DUT and microneedling only

in Progress Pictures 789 upvotes 4 years ago

User Topher1999 achieved hair regrowth using Dutasteride 3 times a week and microneedling with Dr. Pen Ultima A6 every 2 weeks for 9 months. They believe microneedling is the main reason for hairline gains.

community Federal Grant Cuts have impacted PP405 related research

in Technology 458 upvotes 2 months ago

Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

community 8 weeks in with microneedling and minoxidil/tretinoin

in Progress Pictures 95 upvotes 7 months ago

The user is using a combination of microneedling, minoxidil, tretinoin, scalp massages, and red light therapy to address hair loss, with a focus on the hairline and temples. They emphasize the importance of scalp massages and have seen regrowth, attributing success to their comprehensive routine.

community 6 months progress after minoxidil/finasteride stopped working

in Progress Pictures 19 upvotes 1 year ago

A 24-year-old with male pattern baldness experienced side effects from oral finasteride and switched to a topical minoxidil/finasteride combination, later incorporating daily shampooing and scalp brushing to manage hair loss and dandruff. After initial shedding, the regimen led to reduced hair loss and new hair growth, with the user now using a densita mf combination (5% minoxidil/0.1% finasteride + redensyl) nightly.

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