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This study found that obesity, insulin resistance, and hyperandrogenism increase the risk of depression and food cravings in women with PCOS, exacerbating obesity and metabolic syndrome.

This study found a high prevalence of hyperandrogenemia in women with PCOS, with distinct biochemical differences according to BMI and presence of hyperandrogenemia.

This study found that increased serum A4A levels were associated with more severe polycystic ovary syndrome phenotypes and could be a useful marker for biochemical hyperandrogenemia.