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    GlossaryPP405

    novel molecule for treating hair loss by targeting MPC

    PP405 is a novel small molecule developed by Pelage Pharmaceuticals for the treatment of hair loss, specifically targeting mitochondrial pyruvate carrier (MPC).

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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community PP405 Update and My Take on Pelage

      in Research/Science  76 upvotes 2 days ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Can we get a reality check on PP405?

      in Research/Science  79 upvotes 1 week ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community Story time! The Great Unbalding (PP405)

      in Research/Science  227 upvotes 1 week ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.