8 citations
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January 2024 in “Medical Principles and Practice” This study found that silencing IGFBP5 reduced neurotoxicity and motor deficits in the 6-OHDA model of Parkinson's disease, likely by affecting the SHH signaling pathway, suggesting its potential role in mitigating Parkinson’s-related neuronal damage.
22 citations
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August 1999 in “Experimental Dermatology” This study found that subcutaneous injections of guanethidine or 6-hydroxydopamine induced premature hair growth in mice, suggesting a role for sympathetic nerves in hair growth control.
8 citations
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January 2016 in “Cells tissues organs” This study found that chemical sympathectomy inhibited hair follicle growth in mice, suggesting that sympathetic nerves may regulate keratinocyte behavior to promote hair growth.
17 citations
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May 1995 in “Anatomy and Embryology” This study found that treating neonatal mice with the neurotoxin 6-OHDA resulted in temporary hair loss and thinner skin compared to control mice, linking sympathetic neurons to hair growth and skin thickness.
September 2025 in “International Journal of Emergency Medicine” This study reported that the increased dermatological emergency department visits during the pandemic, influenced by PPE usage and psychological stressors, highlight the need for more robust dermatology training and resources in emergency medicine to better prepare for future pandemics.