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    Research 10 of 393

    1. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
    2. Upregulation of mir-1199-5p is associated with reduced type 2 5-α reductase expression in benign prostatic hyperplasia BMC Urology · 2022 · 6 citations
    3. 102 Methylation of CpG islands in promoter of type 2 5-α reductase and implications of finasteride resistance for BPH therapy European Urology Supplements · 2016
    4. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    5. 1424 METHYLATION AND DECREASED EXPRESSION OF 5-ALPHA REDUCTASE 2 IN HUMAN PROSATE SAMPLES: IMPLICATIONS FOR RESISTANCE TO THERAPY FOR BPH The Journal of Urology · 2010
    6. The Biomolecular Effects of Finasteride on Male Rat Brain during Administration and after Discontinuation The World Journal of Men s Health · 2025
    7. The feasibility of quantitative analysis of androgen metabolism by use of single dermal papillae from human hair follicles Experimental Dermatology · 2001 · 4 citations
    8. Finasteride와 저용량 Dutasteride 병용요법으로 호전된 안드로겐성 탈모증 1예 대한피부과학회지 · 2017
    9. Sponsored Lecture 3 : Updates on 5 alpha-rers(5ARIs) for the treatment of male pattern hair loss(MPHL) 프로그램북(구 초록집) · 2014
    10. The effect of finasteride on the male rat brain Research Square (Research Square) · 2023
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    Community 10 of 1000+

    1. 5ar Type I in the frontal hair follicles - Dutasteride Reddit · 30 Apr 2024
    2. Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate. Reddit · 11 May 2023
    3. 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that? Reddit · 3 Oct 2024
    4. Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others. Reddit · 18 May 2023
    5. How come Dut doesn’t cause more brain problems than fin if it inhibits Type 1 5AR? Reddit · 26 Jun 2024
    6. Isn't it kind of strange that hair loss happens at where the 2 main superficial temporal arterty branches (temples and crown) are? Reddit · 8 May 2023
    7. One year on dut 5mg daily as a 19-20 yr old , answering any queries Reddit · 28 Mar 2026
    8. 2 years on 0.5mg Dutasteride Minoxidil + Hair transplant 4000 Grafts Reddit · 14 Apr 2026
    9. Clascoterone 5% Delivers Strong Phase 3 Hair-Growth Results Reddit · 8 Jan 2026
    10. Was scared to try fin and jumped straight to 2.5mg Dut? Reddit · 12 Sept 2026
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    Learn 1

    1. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride