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    Research 10 of 1000+

    1. The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals Brazilian Journal of Medical and Biological Research · 2003 · 17 citations
    2. Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats Frontiers in Pharmacology · 2025 · 2 citations
    3. Risk of Type 2 Diabetes Mellitus in New Users of 5-Alpha Reductase Inhibitors: A Nationwide Historical Cohort Study Yonsei Medical Journal · 2026
    4. Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta) Teratology · 1997 · 67 citations
    5. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
    6. Synthesis and biological evaluation of esters of 16-formyl-17-methoxy-dehydroepiandrosterone derivatives as inhibitors of 5α-reductase type 2 Journal of Enzyme Inhibition and Medicinal Chemistry · 2015 · 5 citations
    7. In Silico Structure-Based Drug Design Approach To Evaluate Quercetin And Kaempferol As Dual Inhibitors Of Jak3 Kinase And 5-Alpha Reductase Type II with ADMET Profiling Zenodo (CERN European Organization for Nuclear Research) · 2026
    8. In Silico Structure-Based Drug Design Approach To Evaluate Quercetin And Kaempferol As Dual Inhibitors Of Jak3 Kinase And 5-Alpha Reductase Type II with ADMET Profiling Zenodo (CERN European Organization for Nuclear Research) · 2026
    9. 1424 METHYLATION AND DECREASED EXPRESSION OF 5-ALPHA REDUCTASE 2 IN HUMAN PROSATE SAMPLES: IMPLICATIONS FOR RESISTANCE TO THERAPY FOR BPH The Journal of Urology · 2010
    10. Genetic analysis of 5 α reductase type 2 enzyme in relation to oxidative stress in cases of androgenetic alopecia in a sample of egyptian population Our Dermatology Online · 2013 · 1 citations
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    Community 10 of 1000+

    1. 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that? Reddit · 3 Oct 2024
    2. Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate. Reddit · 11 May 2023
    3. Was scared to try fin and jumped straight to 2.5mg Dut? Reddit · 12 Sept 2026
    4. 5ar Type I in the frontal hair follicles - Dutasteride Reddit · 30 Apr 2024
    5. My story (22m, fin, min, niz, RU, dut –> part frontal hair system) Reddit · 6 May 2023
    6. Connection between finasteride and nafld? Reddit · 13 Aug 2024
    7. Fun thought experiment about halting hair loss permamently Reddit · 6 May 2024
    8. We need actual hair loss studies on Epristeride Reddit · 23 Oct 2024
    9. The truth about Dutasteride (w/ sources) Reddit · 24 Jan 2023
    10. Thoughts on this Article: Post-Finasteride and Neurological Effects Reddit · 16 Mar 2024
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    Learn 3 of 24

    1. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    2. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    3. Neem Oil Oil from the neem tree, used in traditional remedies
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