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    Research 10 of 1000+

    1. GC-MS Fatty Acid Profile and In silico Studies of Telfairia occidentalis Hook f. (Fluted Pumpkin) and Sphenostylis stenocarpa (African Yam bean) Seeds Oil on Human 5 Alpha Reductase II 2026
    2. Extract of <i>Plumbago zeylanica</i> enhances the growth of hair follicle dermal papilla cells with down‐regulation of 5α‐reductase type II Journal of Cosmetic Dermatology · 2020 · 4 citations
    3. Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids Steroids · 2015 · 13 citations
    4. Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5&alpha;-reductase isoform II inhibition using a cell-free in vitro test system Research and reports in urology · 2016 · 3 citations
    5. Structure of human type II 5 alpha-reductase gene. Endocrinology · 1992 · 124 citations
    6. Expression and Activity Assay of Human Steroid 5 Alpha-Reductase Type II in CHO Cells Pharmaceutical biotechnology · 2004
    7. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997 · 416 citations
    8. Discovery of novel 5α-reductase type II inhibitors by pharmacophore modelling, virtual screening, molecular docking and molecular dynamics simulations Molecular Simulation · 2014 · 5 citations
    9. Rat steroid 5α-reductase kinetic characteristics: Extreme pH-dependency of the type II isozyme in prostate and epididymis homogenates The Journal of Steroid Biochemistry and Molecular Biology · 1995 · 13 citations
    10. Pharmacogenetic analysis of human steroid 5α reductase type II: comparison of finasteride and dutasteride Journal of Molecular Endocrinology · 2005 · 26 citations
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    Community 10 of 1000+

    1. Kintor Pharma Announces Completion of Patient Enrollment in Phase II Clinical Trial of GT20029 for Treatment of Androgenetic Alopecia in China Reddit · 22 Aug 2023
    2. Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery. Reddit · 13 Jul 2024
    3. Dutasteride Literally Saves Your Hair Reddit · 16 Jun 2024
    4. He is claiming, he can treat alopecia Reddit · 5 Jan 2026
    5. Long term finasteride users; Did you notice any improvement after 2 years? Reddit · 11 Apr 2023
    6. New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase Reddit · 22 May 2024
    7. RootBioTec? Basil extract for hair growth Reddit · 15 Mar 2025
    8. 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that? Reddit · 3 Oct 2024
    9. Which Saw Palmetto is good for blocking 5 alpha reductase, Serenoa repens or Chamaerops humilis? Reddit · 26 Jun 2020
    10. Does caffeine inhibit 5-α-reductase? Reddit · 27 Dec 2019
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    Learn 2 of 24

    1. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    2. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
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