18 citations
,
January 2003 in “Gynecological Endocrinology”
In this study, low-dose finasteride (2.5mg/day) significantly reduced hirsutism scores in women over 12 months without significant hormonal changes or serious side effects.
51 citations
,
October 2002 in “European journal of endocrinology”
This study found that both high-dose and low-dose finasteride significantly reduced hirsutism scores in women after 12 months, with the lower dose being safe and cost-effective.
10 citations
,
October 2009 in “Clinical Therapeutics”
This study found that the orally disintegrating tablet and standard tablet formulations of finasteride met bioequivalence criteria in fasting healthy adult male Han Chinese volunteers, although there was a significant difference in time to maximum concentration.
This prospective study reported that 5mg daily oral low-dose minoxidil over 24 weeks led to a high prevalence of hypertrichosis in 93% of male androgenetic alopecia patients, particularly affecting younger individuals, but generally had minimal impact on patients’ quality of life.
A user with aggressive androgenic alopecia is considering increasing their dutasteride dose from 0.5mg to potentially 2.5mg, while already using oral minoxidil, Nizoral, RU-58841, and dermapen. They are seeking advice on the effectiveness and side effects of higher dutasteride doses, with suggestions to consult a dermatologist and consider a higher Nizoral concentration.
OP increased Dutasteride from 0.5mg to 2.5mg daily and added 5mg Oral Minoxidil, seeing progress after one month. They also used Nizoral Ketoconazole shampoo to reduce scalp inflammation.
Oral minoxidil 2.5mg is generally as effective as 5mg for hair loss with fewer side effects, making it a preferred starting dose. Some users experience side effects like dizziness and water retention at 5mg, and switching to topical minoxidil or combining it with finasteride is suggested for better results.
A 34-year-old man plans to reduce his finasteride dose from 1 mg to 0.5mg due to negative side effects like hormonal imbalances and seeks advice on managing these effects and potential alternatives. Suggestions include considering dutasteride as an alternative and noting that a new equilibrium with a reduced dose may take about two weeks.
Taking dutasteride daily at higher doses results in more effective DHT suppression compared to every other day dosing, due to its dose-dependent nature and long half-life. Even at lower doses, dutasteride is more effective than finasteride for hair loss.