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research EFECTO DE LA TESTOSTERONA, 4-HIDROXIANDROSTENDIONA Y FINASTERIDE SOBRE LA HEMOSTASIA EN UN MODELO DE ISQUEMIA/REPERFUSION CORONARIA EN RATA

November 2008

Testosterone, 4-hydroxyandrostenedione, and finasteride affect blood clotting differently in stressed heart conditions.

research Endocrine treatment of benign prostatichypertrophy: Current concepts

11 citations , January 1991 in “Urology”

This article reviews the potential of combining antiandrogenic and antiestrogenic treatments for BPH, highlighting aromatase inhibitors, but presents no new clinical results; further research is needed.

Effects of Chronic Inhibition of Testosterone Metabolism on Cardiac Remodeling After Ischemia/Reperfusion-Induced Myocardial Damage in Gonadectomized Rats

research Effects of chronic inhibition of Testosterone metabolism on cardiac remodeling after ischemia/reperfusion-induced myocardial damage in gonadectomized rats

4 citations , May 2019 in “Biology open”

This study found that while testosterone administration reduced myocardial damage in gonadectomized rats after ischemia/reperfusion injury, Finasteride led to greater improvements, whereas 4-hydroxyandrostenedione worsened outcomes.

11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro

research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro

7 citations , April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology”

This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.

research 5α-Reductase Inhibitors, Chemical and Clinical Models

17 citations , May 1998 in “Steroids”

This study constructed a model to predict finasteride's inhibitory activity on 5α-reductase type 2 and calculated that a 1 μM plasma concentration, after 50 mg administration, matches prostate inhibition levels.

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learn dehydroepiandrosterone

learn Thymosin Beta 4

What is Thymosin Beta 4, and why is it being researched in relation to hair follicle function and regeneration? Thymosin Beta 4 is a peptide being researched for its potential to enhance hair follicle regeneration.
How is Thymosin Beta 4 typically incorporated into experimental or advanced hair growth products? Thymosin Beta 4 is not an ingredient in any approved or regulated hair-loss product — it is an unapproved research peptide (sold online as TB-500). Published hair studies are in rats and mice only, from one research group; there are no human trials, and the same literature reports it can promote tumour growth.
What role does Thymosin Beta 4 play in scalp biology compared to traditional hair loss treatments? Thymosin Beta 4 may enhance scalp biology but lacks extensive clinical validation compared to traditional treatments.
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learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

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community 4 month hair growth update on 1mg Fin and 5mg liquid minoxidil along with HRT

203 upvotes 5 days ago

The user shared a 4-month hair growth update using 1mg finasteride, 5mg liquid minoxidil, and hormone replacement therapy (HRT), reporting significant hair regrowth. They also use a derma stamp, scalp massages, and a DHT-blocking shampoo.

community 4 months on 0.625 mg oral minoxidil & 1 year on 0.5 mg oral finasteride

6 upvotes 5 days ago

The user has been using 0.625 mg oral minoxidil for 4 months and 0.5 mg oral finasteride for a year to address hair thinning, with noticeable regrowth, especially after adding minoxidil. They experienced initial shedding and side effects like libido loss and facial/body hair thinning, and are considering adjusting their finasteride dosage due to side effects.

community 4 months on topical dutasteride and minoxidil

6 upvotes 5 days ago

The conversation is about a 29-year-old's 4-month progress using topical dutasteride and minoxidil for hair loss. Users inquire about the specific products, dosage, and any side effects.

community 4 months 0.5mg fin/ 1ml 5% minox 30 y/o

9 upvotes 6 days ago

A 30-year-old started using 0.5mg finasteride and 5% minoxidil once daily for hair loss, experiencing positive results with minimal side effects after 4 months. The user warns about minoxidil's toxicity to cats.

community 4 months on finasteride only before and after

33 upvotes 1 week ago

The conversation is about using oral finasteride for hair loss treatment. Users discuss dosage, hairline improvement, and side effects like shedding.

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