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Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels

research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels

20 citations, June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery”

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

research Intracrinology and the Skin

82 citations, January 2000 in “Hormone Research in Paediatrics”

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

research Mechanisms of Disease: Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 as a Novel Treatment for Metabolic Syndrome

69 citations, December 2005 in “Nature Clinical Practice Endocrinology & Metabolism”

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells

63 citations, November 1999 in “British journal of dermatology/British journal of dermatology, Supplement”

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

research Exclusive Androgenic Effect of Dehydroepiandrosterone in Sebaceous Glands of Rat Skin

11 citations, August 2000 in “Journal of Endocrinology”

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

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community Debunk the debunk ? - Not sure but this study still exists ...

EraldCoyleLawliet in Research/Science 24 upvotes 3 years ago

The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It highlights a study suggesting that sulforaphane may reduce DHT levels and promote hair growth in mice.

community High Nicotine use and Hair Loss

SpareInsurance in Chat 90 upvotes 5 months ago

Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.

community Dht test results after 1year oral dut

External_Inside3596 in Treatment 12 upvotes 8 months ago

The user is experiencing increased hair shedding after one year of using oral dutasteride. They are seeking opinions on their DHT test results, which show levels below baseline.

community Father has decent amount of hair but im balding ?

monmonoiser in Chat 15 upvotes 1 year ago

A user is concerned about male pattern baldness despite their father having hair. Replies suggest visiting a dermatologist and considering finasteride or dutasteride, as natural methods are ineffective.

community Going to try the theory posted here for the next 3-6 months

xEternex in Treatment 188 upvotes 3 years ago

User xEternex tries hair regrowth with daily broccoli sprouts, apple extract containing procyanidin b2, and microneedling. Others discuss potential issues with the experiment and share their experiences with vegetable consumption and hair growth.

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