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research Studies on Neurosteroids XXV: Influence of a 5α-Reductase Inhibitor, Finasteride, on Rat Brain Neurosteroid Levels and Metabolism

61 citations, September 2008 in “Biological & Pharmaceutical Bulletin”

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

research Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders

82 citations, August 2006 in “Pharmacology, Biochemistry and Behavior”

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

research Effects of Altering Allopregnanolone Levels During Critical Neurodevelopmental Periods on Alcohol Consumption Vulnerability

January 2018

Early NAS level changes affect alcohol consumption vulnerability.

research Relationships Between Cerebrospinal Fluid GABAergic Neurosteroid Levels and Symptom Severity in Men with PTSD

59 citations, November 2018 in “Psychoneuroendocrinology”

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

research Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk

1 citations, January 2019 in “Elsevier eBooks”

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

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Community Join

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community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 8 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community 4 months progress on topicals and vitamins !

in Is this regrowth? 8 upvotes 7 months ago

A 24-year-old male has been using 0.1% finasteride and 5% minoxidil daily for four months, added dermarolling and topical dutasteride, and sees hair regrowth, improving from a Norwood scale 4a to 3a. He wants to optimize his hair loss treatment routine.

community Spironolactone topically with a try ?!

in Research/Science 1 upvotes 9 months ago

A 30-year-old male is considering using dutasteride and fluridil for hair loss maintenance and is curious about the effectiveness of topical spironolactone, as he cannot take finasteride. He is also planning a hair transplant.

community Hair Loss Breakthrough: Keratin Microsphere Gel Initiates Hair Regrowth in Days by Directly Targeting Follicles and Boosting Gene Expression - Gilmore Health News

in Treatment 471 upvotes 8 months ago

A new hair loss treatment involving Keratin Microsphere Gel is discussed, with skepticism and jokes about its effectiveness and comparisons to other treatments. Users are doubtful and make light of the situation, referencing past disappointments and the study's focus on mice.

community I know that wanting a cure is unrealistic and too much to ask. But I at least want medicine that will work reliably for almost everyone.

in Chat 51 upvotes 2 months ago

The conversation is about the effectiveness of hair loss treatments like finasteride, dutasteride, and minoxidil. Users agree these treatments help maintain hair but don't guarantee miraculous regrowth, emphasizing early intervention for best results.

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