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research Causal Relationship Between Blood Metabolomics and Female Pattern Hair Loss: A Bidirectional Mendelian Randomization Study

February 2025 in “Clinical Cosmetic and Investigational Dermatology”

This study used Mendelian randomization to explore associations between 1400 blood metabolites and female-pattern hair loss, finding 23 metabolites and 4 metabolic ratios linked to the condition, while identifying fructose/mannose metabolism as a significant pathway.

research Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK

22 citations , February 2008 in “Journal of Neurochemistry”

This study found that minoxidil prevents long-term serotonergic toxicity induced by MDMA in rats, primarily by opening mitochondrial KATP channels and involving Akt and MAP kinases in its neuroprotective mechanism.

research Bio-Based Electrospun Fibers for Wound Healing

213 citations , September 2020 in “Journal of Functional Biomaterials”

This review discusses bio-based polymers, highlighting their potential in wound healing applications, but reports no new clinical results.

research Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications

421 citations , January 2015 in “Chemical Society Reviews”

This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.

research Minoxidil opens mitochondrial K_ATP channels and confers cardioprotection

28 citations , January 2004 in “British Journal of Pharmacology”

This study found that minoxidil provides cardioprotective effects in guinea-pig heart cells through selective activation of mitochondrial ATP-sensitive potassium channels.

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learn Omega 3

Did you know omega-3 can lower scalp inflammation that leads to sudden hair loss? Omega-3 can reduce scalp inflammation, potentially preventing sudden hair loss.
Is the omega-3 to omega-6 ratio in your diet feeding your hair problem without you knowing? Nutrition sources describe a lopsided omega-6 to omega-3 intake as pro-inflammatory, but no published human study shows that the dietary ratio changes 5-alpha reductase, scalp DHT or hair loss; the one relevant trial tested a commercial omega-3/6 plus antioxidant supplement in 120 women, not a change in dietary fat ratio.
How can omega-3 supplements help reduce hair loss and support healthy hair growth? Omega-3 supplements may reduce hair loss by improving scalp health and circulation.
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community 3 months on Topical Min,Fin,Tre.

34 upvotes 1 day ago

A 47-year-old male is using topical minoxidil, finasteride, and tretinoin for hair loss, showing early progress with plans to continue for 12 months before considering a hair transplant. Users encourage consistency and note visible improvements.

community 3 month Dut .1mg 1.1fin 5mg oral minoxidil plus topical.

21 upvotes 1 day ago

The user started a hair loss treatment in June using 0.1mg dutasteride, 1.1mg finasteride, 5mg oral minoxidil, and topical minoxidil. They report good progress with no significant side effects, except for some unwanted hair growth on the face and hands.

community 3 months on oral minoxidil, scalp itches like crazy

120 upvotes 3 days ago

The conversation discusses using oral minoxidil at 2.5mg for hair growth, causing scalp itchiness and increased body hair. Suggestions include using Nizoral as a DHT blocker, black hair fibers for coverage, and considering finasteride for better results.

community 3 Months and 6 Days After Switching from Finasteride to Dutasteride

4 upvotes 4 days ago

The user switched from finasteride to dutasteride and is experiencing hair thinning and shedding, but is advised to be patient as improvement may take 6-12 months. Others share similar experiences, suggesting that initial shedding is normal and regrowth may occur after several months.

community 3 months of 5mg topical minoxidil

9 upvotes 5 days ago

The user has been using 5% topical minoxidil for nearly three months and is uncertain about the results. Other users suggest adding finasteride or dutasteride to improve hair growth and prevent further hair loss.

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