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research 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling

26 citations , October 2016 in “Biomolecules & Therapeutics”

This study found that 3-Deoxysappanchalcone may stimulate hair growth in mice by promoting proliferation of hair follicle dermal papilla cells through WNT/β-catenin and STAT signaling modulation.

research 010 Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus

1 citations , September 2019 in “Journal of Investigative Dermatology”

This study developed a pemphigus model in mice showing that anti-Desmocollin 3 and anti-Desmoglein 3 antibodies lead to more severe disease, suggesting diverse antigens contribute to varying human pemphigus phenotypes.

research A 4kb Fragment of the Desmocollin 3 Promoter Directs Reporter Gene Expression to Parakeratotic Epidermis and Primary Hair Follicles

1 citations , July 2006 in “Journal of Investigative Dermatology”

A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

research DEVELOPMENT OF A DESMOCOLLIN-3 ACTIVE MOUSE MODEL RECAPITULATING HUMAN ATYPICAL PEMPHIGUS

1 citations , August 2019

In this study, researchers developed a pemphigus mouse model expressing anti-Desmocollin 3 antibodies and found it mimicked atypical pemphigus with distinct pathological features compared to the standard Desmoglein 3 model.

research Case Report: Bi-allelic missense variant in the desmocollin 3 gene causes hypotrichosis and recurrent skin vesicles

August 2022 in “Frontiers in genetics”

This study identified a novel bi-allelic missense variant in the DSC3 gene linked to severe Hypotrichosis with Recurrent Skin Vesicles in a Saudi child, supporting its role in the condition.

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community Shiseido's S-DSC Hair Multiplication Treatment in Japan Available to Foreign Citizens (not cheap)

35 upvotes 1 year ago

Shiseido's S-DSC Hair Multiplication Treatment in Japan is available to foreigners but is expensive and not very effective. Despite past disappointments, there is hope for future treatments with more options in development beyond Minoxidil and Finasteride.

community Weird Hair Loss Pattern – Worth a Biopsy?

in Journals / Progress Pictures 84 upvotes 1 year ago

The user is experiencing a strange hair loss pattern despite using dutasteride for 3 years and minoxidil with tretinoin for 1.5 years. They recently added microneedling and are considering a scalp biopsy to understand the cause.

community Horrible news, Stemson Therapeutics has shut down

193 upvotes 1 year ago

Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

community 3 months on Topical Min,Fin,Tre.

34 upvotes 3 days ago

A 47-year-old male is using topical minoxidil, finasteride, and tretinoin for hair loss, showing early progress with plans to continue for 12 months before considering a hair transplant. Users encourage consistency and note visible improvements.

community 3 month Dut .1mg 1.1fin 5mg oral minoxidil plus topical.

21 upvotes 3 days ago

The user started a hair loss treatment in June using 0.1mg dutasteride, 1.1mg finasteride, 5mg oral minoxidil, and topical minoxidil. They report good progress with no significant side effects, except for some unwanted hair growth on the face and hands.

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Learn

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learn 3 aminopropane Sulfernic acid

learn Omega 3

Can low omega-3 intake after a diet change weaken hair? There is no good evidence that low omega-3 intake causes hair loss or that adding omega-3 restores hair. If hair thinned after a diet change, ask a doctor to check for iron deficiency, low protein or calorie intake, or telogen effluvium.
Can omega-3 calm scalp inflammation and hair shedding? What the evidence says No study has shown that omega-3 lowers scalp inflammation or prevents sudden hair loss. Sudden hair loss needs a doctor to find the cause.
Is the omega-3 to omega-6 ratio in your diet feeding your hair problem without you knowing? Nutrition sources describe a lopsided omega-6 to omega-3 intake as pro-inflammatory, but no published human study shows that the dietary ratio changes 5-alpha reductase, scalp DHT or hair loss; the one relevant trial tested a commercial omega-3/6 plus antioxidant supplement in 120 women, not a change in dietary fat ratio.
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learn acetyl tetrapeptide-3

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