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research Determination of Rat 5α-Reductase Type 1 Isozyme Activity and Its Inhibition by Novel Steroidal Oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research Discovery and Optimization of Novel Pyridines as Highly Potent and Selective Glycogen Synthase Kinase 3 Inhibitors
New pyridine compounds effectively inhibit GSK3, a diabetes treatment target.
research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents
Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
research Design, Synthesis and Anxiolytic Activity Evaluation of N-Acyltryptophanyl-Containing Dipeptides, Potential TSPO Ligands
The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.
research Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
Community Join
5 / 1000+ resultscommunity Is something finally happening here? What do you think?
The conversation discusses hair regrowth using RU58841 and Minoxidil in the morning, and Minoxidil with needle massage in the evening. The user is inquiring if there are signs of hair regrowth by comparing photos from September 3 to recent ones.
community 2 Months 1mg Finasterid daily and Minoxidil 5% twice a day
A 20-year-old male using 1mg finasteride daily and 5% minoxidil twice a day for two months reported significant hair regrowth with no side effects. Users discussed the effectiveness of these treatments, the importance of consulting a doctor, and the potential for continued improvement over time.
community 2 week difference W/ micro needle, RU58841, oral minox 2.5, topical minox, ketoconazole shampoo, and dutasteride.
The conversation is about hair regrowth using micro-needling, RU58841, oral and topical minoxidil, ketoconazole shampoo, and dutasteride. Users suggest that noticeable results take longer than two weeks, though one user mentions seeing baby hairs.
community 2 months on Fin/Min + Topical Minoxidil at 34 years old
The user started oral finasteride and minoxidil, along with topical minoxidil, and saw encouraging hair regrowth results after two months without side effects. Some users reported side effects like depression and low sex drive from finasteride, while others shared positive experiences with varying dosages.
community 2.5 months of topical Finasteride
A user reported significant hair regrowth using a homemade 0.01% topical finasteride solution, highlighting its effectiveness and lack of side effects. The discussion included concerns about oral finasteride's side effects and the benefits of topical solutions.