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diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties
Research
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research Determination of Rat 5α-Reductase Type 1 Isozyme Activity and Its Inhibition by Novel Steroidal Oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents
Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.
research Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Androgen Receptor Antagonists Structure-Activity Relationships
Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
Community Join
5 / 1000+ resultscommunity Is something finally happening here? What do you think?
The conversation discusses hair regrowth using RU58841 and Minoxidil in the morning, and Minoxidil with needle massage in the evening. The user is inquiring if there are signs of hair regrowth by comparing photos from September 3 to recent ones.
community 2 year anniversary of Fin only - M48
A 48-year-old man has been using finasteride at 1mg three times a week for two years, seeing some hair regrowth but noting lighting affects appearance. He is considering adding minoxidil but is concerned about shedding.
community 2 months into Minoxidil, poor sleep however, is it over for me?
A 21-year-old university student started using Minoxidil and derma stamping for hair loss over two months ago. Despite poor sleep due to exams, the student is hopeful about improving their sleep schedule during the holidays and notes their hairline remains straight.
community 2 years of dut, great result i’ve seen, hairline is coming back
The conversation is about a user sharing positive results from using dutasteride for hair regrowth over two years, with others discussing the effectiveness and experiences with hair loss treatments like finasteride and minoxidil. Some users request before-and-after photos to assess the effectiveness of the treatment.
community 2 Years on Fin + Min, No Improvement, Hair Worse Than Before
A user has been using Minoxidil and Finasteride for 2 years without improvement, experiencing worsening hair loss. They are considering other treatments like Dutasteride, PRP, and microneedling.