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research Increased 25(OH)D3 level in redheaded people: Could redheadedness be an adaptation to temperate climate?

5 citations , June 2020 in “Experimental dermatology”

This study found that redheaded individuals had higher levels of vitamin D precursor 25(OH)D3 compared to non-redheaded individuals, suggesting a physiological adaptation to low UVB radiation in Europe.

Segmental Analysis of Human Hair Reveals Intra-Annual Variation in 25(OH)D3 Concentrations in Modern and Archaeological Individuals

research Segmental analysis of human hair reveals intra-annual variation in 25(OH)D3 concentrations in modern and archaeological individuals

January 2025 in “Scientific Reports”

This study explored 25-hydroxyvitamin D3 levels in hair samples from participants in Aberdeen and suggested potential links between hair vitamin D levels, seasonal UVB exposure, and marine diet in both modern and archaeological contexts.

research An unusual presentation of vitamin D dependent rickets type 2 with low 25 (OH) D3 levels and alopecia: a case report of two siblings

July 2022 in “International Journal of Contemporary Pediatrics”

This report describes siblings with vitamin D-dependent rickets type 2, characterized by growth retardation, alopecia totalis, and low 25(OH)D3 levels, highlighting its autosomal recessive pattern and distinction from other rickets types.

research 1α,25(OH)2-Dihydroxyvitamin D3/VDR protects the skin from UVB-induced tumor formation by interacting with the β-catenin pathway

45 citations , September 2012 in “The Journal of Steroid Biochemistry and Molecular Biology”

This study found that deleting β-catenin in epidermis-specific VDR knockout mice did not prevent UVB-induced skin tumors, indicating β-catenin does not compensate for VDR's role in tumor suppression.

research Evidence for 1,25-Dihydroxyvitamin D3-independent Transactivation by the Vitamin D Receptor

36 citations , February 2007 in “Journal of biological chemistry/The Journal of biological chemistry”

This study found that vitamin D receptor activation in primary keratinocytes can occur independently of the 1,25-dihydroxyvitamin D₃ ligand, likely through interaction with retinoid X receptors.

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community UPDATE - 7 months 2,5 dutatesteride

10 upvotes 1 year ago

The user continues to experience hair loss despite using dutasteride 2.5mg, minoxidil 5mg, and ciclopirox shampoo, and plans to reassess after one year. Others report similar issues with dutasteride, with some switching to finasteride or adding RU58841.

community Husband’s 2.5 month progress so far - I’m amazed!!

354 upvotes 1 year ago

A husband saw significant hair regrowth in 2.5 months using minoxidil, finasteride, collagen, biotin, multivitamins, GHK-cu, microneedling, and scalp oils. His wife highlighted the routine's effectiveness and the importance of consistency.

community Topical fin (0.1%) and min (5%) for almost 2 years

in Progress Pictures 11 upvotes 3 months ago

A 25-year-old male has been using topical finasteride (0.1%) and minoxidil (5%) for almost two years with no visible improvement but stable hair loss. Suggestions include switching to oral finasteride and minoxidil, considering stronger treatments like dutasteride, and consulting a doctor for personalized advice.

community 4 month update Fin/Min/Dermatamp

28 upvotes 1 year ago

The user reported gradual hair regrowth after 4 months using oral finasteride, topical minoxidil, dermastamping, and vitamins C and D3. They noted the use of a 1.25mm dermastamp and discussed sourcing finasteride in Canada.

community My estrogen levels are obscene

6 upvotes 1 year ago

A 30-year-old male using finasteride for hair loss has high testosterone and estrogen levels but no side effects. He is advised to monitor hormone levels, consider dietary changes, and use additional treatments like vitamin D3, minoxidil, and dutasteride for hair growth.

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