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Rickets with Alopecia: Remission Following a Course of 1-Alpha-Hydroxy Vitamin D3 Therapy

research Rickets with alopecia-remission following a course of 1-?-hydroxy vitamin D3 therapy

6 citations , August 1989 in “European journal of pediatrics”

This case study describes a child with rickets and alopecia who responded to a small dose of 1-a-hydroxyvitamin D3, but her alopecia remained unchanged despite treatment.

25 Hydroxyvitamin D 1 Alpha-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis

research 25 Hydroxyvitamin D 1 α-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis

140 citations , April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that mice lacking the 1αOHase enzyme, which is responsible for producing a key vitamin D metabolite, showed impaired epidermal differentiation and delayed recovery of skin barrier function after disruption.

research The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3

37 citations , August 2015 in “The Journal of Steroid Biochemistry and Molecular Biology”

This study found that in a mouse model with hereditary 1,25-dihydroxyvitamin D resistant rickets, a mutant vitamin D receptor lacking hormone-binding ability could restore normal hair cycling and affect parathyroid hormone regulation.

research Evidence for 1,25-Dihydroxyvitamin D3-independent Transactivation by the Vitamin D Receptor

36 citations , February 2007 in “Journal of biological chemistry/The Journal of biological chemistry”

This study found that vitamin D receptor activation in primary keratinocytes can occur independently of the 1,25-dihydroxyvitamin D₃ ligand, likely through interaction with retinoid X receptors.

research 211 Effect of 1α,25-dihydroxyvitamin D3 on mechanical properties of hairless mouse skin

June 1996 in “Journal of Dermatological Science”

Vitamin D3 applied to mouse skin caused more wrinkles and sagging due to changes in the skin's outer layer.

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community 4 month update Fin/Min/Dermatamp

28 upvotes 1 year ago

The user reported gradual hair regrowth after 4 months using oral finasteride, topical minoxidil, dermastamping, and vitamins C and D3. They noted the use of a 1.25mm dermastamp and discussed sourcing finasteride in Canada.

community Topical fin (0.1%) and min (5%) for almost 2 years

in Progress Pictures 11 upvotes 3 months ago

A 25-year-old male has been using topical finasteride (0.1%) and minoxidil (5%) for almost two years with no visible improvement but stable hair loss. Suggestions include switching to oral finasteride and minoxidil, considering stronger treatments like dutasteride, and consulting a doctor for personalized advice.

community Naturally high T (1,100+) causing diffuse thinning while on Dut

22 upvotes 5 months ago

A 26-year-old male with high testosterone is experiencing diffuse hair thinning despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy. Suggestions include adjusting dutasteride dosage, monitoring iron levels, and consulting a dermatologist for further evaluation.

community DHT results after 1 year on dutasteride, confused and seeking guidance

in Finasteride/Dutasteride 107 upvotes 1 year ago

The user is experiencing rapid hair loss despite using dutasteride, finasteride, and minoxidil, and is concerned about high estradiol and testosterone levels. They are advised to consult an endocrinologist for potential hormonal imbalances.

community Progress- 3 months, 5% Minoxidil, 0.1% Finasteride

in Is this regrowth? 232 upvotes 1 year ago

The user experienced significant hair loss after stopping a treatment of 5% Minoxidil and 0.1% Finasteride, which they had used from December 2021 to January 2024. They resumed the treatment in April 2025, hoping for regrowth, and are considering additional treatments like transplants and steroid injections.

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