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research Hormone therapy in acne

24 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

This review examines hormonal influences on acne development and available hormonal therapies but reports no new clinical results.

research Roles of Type 10 17beta-Hydroxysteroid Dehydrogenase in Intracrinology and Metabolism of Isoleucine and Fatty Acids

26 citations , March 2006 in “Endocrine, metabolic & immune disorders. Drug targets”

This article discusses the functions of the enzyme 17beta-HSD10, including its role in steroid metabolism and potential links to Alzheimer's disease, but reports no new experimental findings.

research 17 beta-hydroxysteroid dehydrogenase 3 deficiency in the Mediterranean population.

46 citations , August 2006 in “PubMed”

In this study, researchers identified and examined males with 17 beta-HSD3 deficiency in a highly inbred Arab population, noting genetic findings and the progression of male characteristics despite being raised as females initially.

research Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women

28 citations , August 2003 in “Steroids”

This study found that untreated hirsute patients have lower expression of type 2 17β-HSD mRNA in scalp hairs, indicating potential disturbances in androgen metabolism, compared to treated hirsute patients.

research Structure and Expression of a New Complementary DNA Encoding the almost Exclusive 3β-Hydroxysteroid Dehydrogenase/Δ⁵-Δ⁴-lsomerase in Human Adrenals and Gonads

354 citations , August 1991 in “Molecular Endocrinology”

This study found that distinct isoenzymes of 3 beta-hydroxysteroid dehydrogenase are expressed in human adrenals and gonads compared to the placenta and skin.

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community Has there been any update or progress on the 3-alpha hydroxysteroid dehydrogenase hypothesis?

13 upvotes 2 months ago

The conversation discusses the hypothesis that a lack of the enzyme 3-alpha hydroxysteroid dehydrogenase (3α-HSD) on the scalp may contribute to hair loss by allowing DHT to accumulate. Despite interest in this theory, no recent research has been conducted, and current treatments like finasteride and minoxidil remain the most supported options.

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