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research Pharmacology of Antiandrogens

97 citations , November 1986 in “Journal of Steroid Biochemistry”

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Sex Hormones and Antiandrogens Influence In Vitro Growth of Dermal Papilla Cells and Outer Root Sheath Keratinocytes of Human Hair Follicles

research Sex Hormones and Antiandrogens Influence In Vitro Growth of Dermal Papilla Cells and Outer Root Sheath Keratinocytes of Human Hair Follicles

12 citations , July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology”

Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.

research Androgen Receptor Antagonists Structure-Activity Relationships

204 citations , February 2000 in “Current Medicinal Chemistry”

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

research Mechanism of Action of Herbs and Their Active Constituents Used in Hair Loss Treatment

47 citations , August 2016 in “Fitoterapia”

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

research Adrenal Steroid Precursors Exert Potent Androgenic Action in the Hamster Sebaceous Glands of Flank Organs and Ears

8 citations , May 1996 in “Endocrinology”

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

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community Clinical Trial: Clascoterone (Cortexolone 17A-Propionate)

in Research/Science 24 upvotes 1 year ago

A user is joining a clinical trial for Clascoterone, a drug approved for acne but being tested for hair loss. They previously tried finasteride with limited success and plan to share updates on their experience with the new treatment.

community Anyone here who’s using Alfatradiol (17a-Estradiol) in consistency with some results?

in Treatment 7 upvotes 4 years ago

User discusses Alfatradiol (17a-Estradiol) as a potential hair loss treatment with mixed results. Concerns include low dosage, receptor theory, and possible increased aromatase activity on scalp.

community I live in the US. Where are most reputable places to purchase either Alfatradiol or Pyralutamide?

in Product 3 upvotes 10 months ago

The user is considering adding Alfatradiol or Pyralutamide to their current hair loss treatment of oral Dutasteride and Minoxidil. They are seeking advice on experiences and purchasing options for these products in the US.

community Alfatradiol is a topical 5AR inhibitor that this study shows is effective in stopping hair loss without sides. It can be bought OTC in Europe right now. Thoughts?

12 upvotes 9 years ago

Hair loss treatments, specifically the use of Alfatradiol as an over-the-counter topical 5AR inhibitor that has been shown to be effective in stopping hair loss without side effects. Other treatments discussed include Minoxidil, finasteride and RU58841.

community Hypothetically, if estradiol has been a "cure" for hair loss, could one apply estradiol topically and just take an estrogen blocker and/or testosterone to offset the systematic effects?

in Research/Science 7 upvotes 5 months ago

Topical estradiol may help with hair loss but can have systemic effects, like reduced testosterone production. Using estrogen blockers can have negative side effects, such as joint pain and reduced sex drive.

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