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research Pharmacology of different progestogens: the special case of drospirenone

104 citations , January 2005 in “Climacteric”

This review discusses the pharmacological properties of progestins used in contraception and hormone replacement therapy, focusing on drospirenone's unique effects, but reports no new experimental findings.

Activity of 17β-(N-Alkyl/Arylformamido) and 17β-[(N-Alkyl/Aryl) Alkyl/Arylamido]-4-Methyl-4-Aza-5α-Androstan-3-Ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear

research Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche.

10 citations , August 1998 in “Journal of Investigative Dermatology”

This study observed that the compound EM-402 reduced 5α-reductase activity and sebaceous gland size in the flank organs and ears of hamsters, indicating potent localized anti-androgenic effects without systemic action.

research Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity

37 citations , November 1995 in “Journal of Investigative Dermatology”

This study found that topical finasteride and flutamide both significantly reduced sebaceous gland growth and decreased prostatic weights in hamsters, indicating systemic effects despite local application.

research Profile of the progesterone derivative chlormadinone acetate — Pharmocodynamic properties and therapeutic applications

33 citations , January 2009 in “Contraception”

This review summarizes the use of chlormadinone acetate for hormone replacement therapy and contraception, highlighting its anti-androgenic effects, contraceptive efficacy, and clinical tolerability, without offering new clinical results.

research Molecular interactions of natural and synthetic steroids in female hamsters’ flank organs

1 citations , March 2012 in “Journal of Dermatological Science”

This study found that various steroids affected the mRNA expression of enzymes involved in lipid metabolism in hamster flank organs, with different impacts depending on the steroid and combination used.

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community Reversing Hairloss with 7α-Methyl-19-Nortestosteron aka Trestolone

7 upvotes 1 year ago

The user experienced significant hair regrowth using Trestolone, GHK-Cu, and Minoxidil. They avoided Finasteride due to concerns about side effects and noted that their approach reduced androgenic load, contributing to hair regrowth.

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