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17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome

research 17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome

42 citations, September 2007 in “The Journal of Clinical Endocrinology and Metabolism”

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

research Detection of Urine Metabolites in Polycystic Ovary Syndrome by UPLC Triple-TOF-MS

23 citations, June 2015 in “Clinica Chimica Acta”

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

research Heterozygous 21-Hydroxylase Deficiency as a Cause of Hyperandrogenism

1 citations, August 2012 in “Journal der Deutschen Dermatologischen Gesellschaft”

A woman's hyperandrogenism was caused by a genetic mutation leading to non-classic adrenogenital syndrome.

research Ketoconazole Therapy for Women with Acne and/or Hirsutism

46 citations, August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

research Female Pattern Hair Loss in a Patient with 17α-Hydroxylase Deficiency

4 citations, January 2010 in “Acta dermato-venereologica”

Low androgen levels can still cause female pattern hair loss.

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Community Join

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community Clinical Trial: Clascoterone (Cortexolone 17A-Propionate)

in Research/Science 24 upvotes 7 months ago

A user is joining a clinical trial for Clascoterone, a drug approved for acne but being tested for hair loss. They previously tried finasteride with limited success and plan to share updates on their experience with the new treatment.

community Anyone here who’s using Alfatradiol (17a-Estradiol) in consistency with some results?

in Treatment 7 upvotes 3 years ago

User discusses Alfatradiol (17a-Estradiol) as a potential hair loss treatment with mixed results. Concerns include low dosage, receptor theory, and possible increased aromatase activity on scalp.

community I live in the US. Where are most reputable places to purchase either Alfatradiol or Pyralutamide?

in Product 3 upvotes 1 week ago

The user is considering adding Alfatradiol or Pyralutamide to their current hair loss treatment of oral Dutasteride and Minoxidil. They are seeking advice on experiences and purchasing options for these products in the US.

community Alfatradiol is a topical 5AR inhibitor that this study shows is effective in stopping hair loss without sides. It can be bought OTC in Europe right now. Thoughts?

12 upvotes 8 years ago

Hair loss treatments, specifically the use of Alfatradiol as an over-the-counter topical 5AR inhibitor that has been shown to be effective in stopping hair loss without side effects. Other treatments discussed include Minoxidil, finasteride and RU58841.

community 10 months CB and Oral Minoxidil

in Progress Pictures 112 upvotes 7 months ago

A person with Alopecia Areata on their beard is using CB-03-01 and oral minoxidil for treatment. Some users question the effectiveness of CB-03-01 for beard hair, suggesting that minoxidil alone may be responsible for any observed hair growth.

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