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research 17α-Acetoxy-6-Bromo-16β-Methylpregna-4,6-Diene-3,20-Dione: A New Steroidal Derivative with High Antiandrogenic Activity

December 1998 in “Acta Crystallographica Section C-crystal Structure Communications”

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

research Androgenic and Anti-Androgenic Effects of Progesterone Derivatives with Different Halogens as Substituents at the C-6 Position

19 citations , June 1999 in “Steroids”

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

research Androgen Antagonists in Androgen Target Tissues

27 citations , January 1984 in “Pharmacology & Therapeutics”

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

research The First Syntheses of 16β-Chloro- and 16β-Bromo-Cyproterone Acetate

3 citations , January 2003 in “Synthetic Communications”

Scientists made two new chemicals that might help treat diseases caused by male hormones.

research Recent Advances in Oxasteroids Chemistry

41 citations , March 2007 in “Steroids”

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

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community Alfatradiol Experience (2 months)

in Treatment 12 upvotes 4 years ago

User experienced side effects from oral finasteride and tried topical Alfatradiol for hair loss. Alfatradiol provided maintenance without significant regrowth, and user suggests it as an alternative for those struggling with finasteride side effects.

community Anyone here who’s using Alfatradiol (17a-Estradiol) in consistency with some results?

in Treatment 7 upvotes 4 years ago

User discusses Alfatradiol (17a-Estradiol) as a potential hair loss treatment with mixed results. Concerns include low dosage, receptor theory, and possible increased aromatase activity on scalp.

community Alfatradiol is a topical 5AR inhibitor that this study shows is effective in stopping hair loss without sides. It can be bought OTC in Europe right now. Thoughts?

11 upvotes 9 years ago

Hair loss treatments, specifically the use of Alfatradiol as an over-the-counter topical 5AR inhibitor that has been shown to be effective in stopping hair loss without side effects. Other treatments discussed include Minoxidil, finasteride and RU58841.

community I think it’s time to drop Pyrilutamide at this point?….

in Update 33 upvotes 3 years ago

A user who has been using Pyrilutamide for 5 months with no results, and other users suggesting they switch to RU58841 or stick to their treatment plan for at least one year.

community Clinical Trial: Clascoterone (Cortexolone 17A-Propionate)

in Research/Science 24 upvotes 1 year ago

A user is joining a clinical trial for Clascoterone, a drug approved for acne but being tested for hair loss. They previously tried finasteride with limited success and plan to share updates on their experience with the new treatment.

View more "17a-acetoxy-6-bromo-16v-methylpregna-4 6-diene-3 20-dione" in community →