27 citations
,
May 1976 in “PubMed” This study concluded that wedge resection in patients with polycystic ovary syndrome did not significantly affect androgen status or the biochemical features of the condition, though most regained regular menstrual cycles and some became pregnant.
9 citations
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August 1952 in “The Journal of Clinical Endocrinology & Metabolism” This study describes a method to estimate endogenous hormone production by neutralizing an endogenous hormone with an oppositely acting hormone.
60 citations
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September 1979 in “Fertility and sterility” This study found that spironolactone reduced testosterone production and urinary 17-ketosteroid excretion, leading to a decrease in hair growth rate and a change in hair texture in women.
6 citations
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September 2024 in “Metabolism and Target Organ Damage” This review discusses the role of skin enzymes in drug metabolism and emphasizes the need for models assessing enzyme activity to evaluate the safety and bioequivalence of topical generic drugs, highlighting efforts to standardize testing protocols for transdermal products.
51 citations
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May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” This review examines the role of steroidal inhibitors in treating prostatic diseases but presents no new clinical results.