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This study found that glioblastoma cells express key enzymes involved in androgen synthesis, suggesting these enzymes might be potential targets for new therapeutic strategies.

This study found that diagnosing nonclassic congenital adrenal hyperplasia in women based solely on serum 17OHP measurements can lead to false positives, suggesting the need for urinary steroid profiles and genetic testing for confirmation.

This study shows that measuring 17-hydroxyprogesterone concentrations in scalp hair may be a useful noninvasive tool for monitoring treatment in adults with congenital adrenal hyperplasia.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

This review examines recent research on optimizing the structures of steroidal inhibitors for key steroidogenic enzymes used as cancer treatments, reporting on 209 new compounds with preclinical data that suggest structural modifications hold promise for developing new antineoplastic agents.