Zone 1 Hepatocellular Necrosis: A Manifestation of Selenium Toxicity?

A 36-year-old man with androgenetic alopecia suspects copper and zinc deficiencies may be accelerating hair loss and is supplementing copper to address this. He is also monitoring blood sugar levels due to previous prediabetes concerns and plans to test for insulin resistance.

Selenium sulfide shampoo helped with a sore scalp but may cause hair root damage. Users experienced hair loss with selenium sulfide and ketoconazole, suggesting reducing use if hair loss occurs.

The user is experiencing significant hair shedding and suspects it may be due to low serum ferritin levels rather than worsening androgenetic alopecia. They have resumed iron supplementation and are seeking additional solutions to address the shedding.

Zinc supplementation caused significant hair shedding for the user, who had been successfully managing hair loss with finasteride, minoxidil, RU58841, and microneedling. The user discontinued zinc after noticing no libido increase and believes the hair loss was due to zinc's interaction with other minerals or hormonal changes.

Low ferritin levels may contribute to hair loss, and raising ferritin above 40 or 70 ng/mL might help with hair regrowth. Some users also consider zinc deficiency and absorption issues as potential factors.

The user is exploring hair loss treatments in China, currently using finasteride and minoxidil, and is concerned about seborrheic dermatitis. Clinics are recommending selenium sulfide, doxycycline, and mesotherapy ampoules like PT88/PT66 or SP88/SP66, but the user is unsure about their effectiveness.