Endoplasmic Reticulum in Health and Disease: The 12th International Calreticulin Workshop, Delphi, Greece

This article reviews the multifunctional roles of calreticulin outside the ER and highlights its impact on wound healing in animal models, but reports no new clinical results.

This study found that calretinin immunoreactivity may help identify the innermost cell layer of the outer root sheath in anagen hair follicles and certain cutaneous adnexal proliferations with follicular, sebaceous, and eccrine differentiation.

This study found that immunohistochemistry for calretinin may identify certain cutaneous adnexal tumors with follicular differentiation towards cells of the outer root sheath.

This study found that the application of calreticulin significantly improved wound healing time and quality in diabetic mice, suggesting it may be an effective topical treatment for chronic wounds.

Calretinin identifies the companion cell layer in human hair follicles.