Nerve-Mediated Expression of Histone Deacetylases Regulates Limb Regeneration in Axolotls

    February 2019 in “ Developmental Biology ”
    Mu‐Hui Wang, Cheng-Han Wu, Ting‐Yu Huang … Mei–Hsuan Lee
    Studysummary This study found that nerve-mediated HDAC1 expression is necessary for blastema formation and limb regeneration in axolotls, and that inhibiting HDACs delays or inhibits this process.
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    Research cited in this study 1

    1. Disrupted Ectodermal Organ Morphogenesis in Mice with a Conditional Histone Deacetylase 1, 2 Deletion in the Epidermis Journal of Investigative Dermatology · 2013