What’s Diet Got to Do With It? Basic and Clinical Science Behind Diet and Acne

July 2022 in “ Cutis ”

Melissa Dodds, Apple A. Bodemer, Bridget E. Shields

acne diet high glycemic index dairy fatty foods mammalian target of rapamycin complex 1 mTORC1 insulin insulin-like growth factor 1 IGF-1 high GI foods

TLDR Diet may influence acne development.

The document discussed the relationship between diet and acne, particularly in Western societies where high glycemic index dairy and fatty foods are prevalent. Although large, blinded, randomized controlled trials were difficult to conduct, early evidence from small clinical trials and larger observational studies suggested that diet played a role in acne pathogenesis. The article focused on the mammalian target of rapamycin complex 1 (mTORC1) pathway, which promoted cellular growth and proliferation and was regulated by nutrient availability, insulin, and insulin-like growth factor 1 (IGF-1).

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