Hyperprolactinemia in Patients with High TSH Levels with Both Clinical and Subclinical Hypothyroidism

    Jyotindra Kumar Sahu, M Ravikant, A. K. Thakur
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    Studysummary This study found that serum prolactin levels were significantly higher in patients with subclinical and clinical hypothyroidism compared to controls, indicating altered prolactin regulation in these patients.
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    The study "Hyperprolactinemia in patients with high TSH levels with both clinical and subclinical hypothyroidism" involved 138 patients with thyroid-related issues. The research found that serum prolactin levels were significantly increased in both subclinical (28.7 ± 6.4 ng/mL) and clinical hypothyroidism (15.02 ± 4.2ng/mL) compared to controls. Hyperprolactinemia was observed in 22.9% of patients with subclinical hypothyroidism and 8.3% of patients with clinical hypothyroidism. The study concluded that prolactin regulation is altered in patients with both clinical and subclinical hypothyroidism, suggesting that thyroid function tests should be conducted in patients with hyperprolactinemia before performing further tests.
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