Vogt-Koyanagi-Harada Disease With Oral Manifestations: A Rare Case Report
January 2026
in “
Contemporary Clinical Dentistry
”
Studysummary This case report describes a rare instance of Vogt-Koyanagi-Harada disease in a 21-year-old Asian woman, highlighting unusual oral manifestations such as tooth discoloration and misalignment, which expand the known clinical spectrum of the disorder.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This case report describes a rare occurrence of Vogt-Koyanagi-Harada disease (VKHD) with oral manifestations in a 21-year-old female. VKHD is a chronic autoimmune disorder that typically affects ocular, dermatological, and auditory systems, but oral involvement is rare. The patient showed symptoms including vitiligo, alopecia, and enamel hypoplasia, with a genetic mutation in the CNNM4 gene identified. The report highlights the need to recognize atypical VKHD presentations for effective management and suggests a possible link between VKHD and oral health, indicating a need for further research.
