The Role of Vitamin D3 Deficiency and Colonization of the Oral Mucosa by Candida Yeast-like Fungi in the Pathomechanism of Psoriasis

This review explores the role of vitamin D3 deficiency and the colonization of the oral mucosa by Candida yeast-like fungi in the pathogenesis of psoriasis. It highlights that vitamin D3 deficiency can exacerbate psoriasis by disrupting the microbiological balance, promoting the overgrowth of Candida fungi. Psoriasis patients, who often have a compromised skin barrier, are more susceptible to fungal infections like Candida, which can further complicate their condition. Additionally, the chronic inflammation associated with psoriasis can lead to metabolic syndrome, creating a cycle that worsens the disease. The review underscores the importance of maintaining vitamin D3 levels to support immune function and prevent fungal overgrowth.