TLDR Higher doses of the medication valproate can cause hair loss, which may stop when the dose is lowered or the medication is stopped.
The document from 2015 reported three cases of alopecia (hair loss) in patients who were treated with sodium valproate for mental disorders. The alopecia appeared after long-term exposure to high plasma concentrations of valproate (approximately 100 µg/ml). However, the hair loss resolved in all cases after the dose was reduced or the treatment was discontinued. The study concluded that alopecia may develop in patients with chronic exposure to high plasma concentrations of valproate. Therefore, patients with high plasma concentrations of valproate should be closely monitored for side effects, particularly alopecia.
17 citations,
January 2013 in “Indian Journal of Pharmacology” High levels of the seizure medication sodium valproate can cause hair loss.
63 citations,
March 2000 in “Annals of clinical psychiatry” Some psychiatric medications can cause hair loss, but it usually grows back after adjusting the medication.
79 citations,
January 2000 in “Annals of Clinical Psychiatry” Some psychiatric medications can cause hair loss, but stopping or reducing the dose usually reverses it.
38 citations,
September 1996 in “Annals of Clinical Psychiatry” Hair loss from mood stabilizers is common but can be managed without stopping the medication.
1 citations,
January 2017 in “Journal of Clinical and Diagnostic Research” Sodium valproate can cause reversible hair loss in some patients.
9 citations,
January 2015 in “Indian Journal of Pharmacology/The Indian journal of pharmacology” Higher doses of the medication valproate can cause hair loss, which may stop when the dose is lowered or the medication is stopped.
9 citations,
October 2012 in “Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology” Stopping the drug olanzapine can reverse hair loss caused by it.
