TLDR Treatment with prednisolone and dapsone stopped new blisters and partially healed previous ones.
A 68-year-old woman presented with mucous membrane pemphigoid, characterized by recurrent mucocutaneous blisters and progressive scalp hair loss over several years. Initially, she experienced tense blisters on her back, chest, and arms, which later involved her oral cavity and scalp, leading to painful erosions and cicatricial alopecia. Histological examination revealed subepidermal bullae with eosinophilic infiltrate, and direct immunofluorescence confirmed the diagnosis. Treatment with prednisolone and dapsone halted the formation of new blisters, and partial healing of previous erosions was observed after 3 months.
15 citations
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November 1998 in “Australasian Journal of Dermatology” Cicatricial pemphigoid rarely affects the scalp but is hard to treat when it does.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
291 citations
,
January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
November 2019 in “Harper's Textbook of Pediatric Dermatology” The document is a detailed medical reference on skin and genetic disorders.
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,
June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
157 citations
,
August 2010 in “Lupus” The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.