Successful Treatment of Alopecia Areata-Associated Trachyonychia With Baricitinib

    March 2024 in “ International Journal of Dermatology ”
    Petra Rózsa, Döníz Degovics, Eszter Baltás, Rolland Gyulai, Lajos Kemény
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    TLDR Baricitinib improved nail condition and hair regrowth in a patient with alopecia and nail abnormalities.
    The document discusses a case study of a 40-year-old male patient with alopecia universalis (AU) and trachyonychia, a condition causing thin, ridged nails. The patient was treated with baricitinib, a medication approved for treating AU, at a dose of 4 mg daily. After 3 months, improvement in the nail symptoms was observed, and after 6 months, almost complete clearance of the nail abnormalities was achieved. Additionally, patchy hair regrowth on the scalp, eyebrows, and eyelashes was observed, and the patient's gingivitis resolved. The treatment significantly improved the patient's quality of life. The document suggests that baricitinib could be a promising treatment for trachyonychia associated with AU.
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