Tooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release

    December 2019 in “ Stem Cell Reviews and Reports
    Delan Huang, Jianhan Ren, Runze Li, Chenyu Guan, Zhicai Feng, Baicheng Bao, Weicai Wang, Chen Zhou
    TLDR Tooth regeneration could become possible by controlling how and when bioactive factors are released.
    The document reviewed the progress in tooth regeneration research, highlighting its advantages over traditional oral restoration treatments. It emphasized the importance of understanding the spatial-temporal expression of cytokines, growth factors, and other bioactive factors during tooth development. The study noted that recent advancements in the technology for spatial-temporal control of drug release made it more feasible to mimic these patterns for effective tooth regeneration. The article discussed the potential future of tooth regeneration by leveraging these developments in bioactive factor release.
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