An inductive signalling network regulates mammalian tooth morphogenesis with implications for tooth regeneration

The document reviewed the complex network of inductive signalling pathways, including BMPs, Wnt, Notch, Shh, and FGF, that regulated tooth morphogenesis in mammals. It highlighted the importance of these pathways in controlling cell proliferation, differentiation, and organogenesis through epithelial–mesenchymal interactions. The study aimed to enhance the understanding of tooth regeneration and offered insights into potential therapeutic strategies for dental abnormalities like tooth agenesis and supernumerary teeth.