Thyroid Disease in Alopecia Areata, Lichen Planopilaris, and Frontal Fibrosing Alopecia: A Case Control Study of 144 Patients

January 2016 in “ US endocrinology ”

Thu Quynh Nguyen, Monica Tsai, Tristan Grogan, Carolyn Goh

alopecia areata frontal fibrosing alopecia lichen planopilaris thyroid disease thyroid dysfunction

TLDR Alopecia is not a significant predictor of thyroid disease when age and sex are considered.

In a retrospective analysis of 144 patients with alopecia conducted from September 2010 to July 2013, it was found that thyroid disease was present in 16.0% of alopecia areata patients, 25.0% of frontal fibrosing alopecia patients, and 17.1% of lichen planopilaris patients, compared to 15.1% of control patients. However, after adjusting for age and sex, alopecia was not a significant predictor of thyroid disease. Despite the rates of thyroid dysfunction in alopecia patients being higher than the general U.S. population, there were no significant differences when compared to the control group.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community How essential is scalp biopsy when dealing with hair loss?

in Treatment 6 upvotes 1 month ago

The user experienced hair loss despite using Fin and Min for 12 years and switched to Dutasteride, RU58841, and Keto scalp serum, but shedding and itch persist. They are considering increasing Dutasteride to 2.5mg and questioning the necessity of a scalp biopsy, with mixed opinions on its usefulness.

community scarring alopecia awareness in this community

in Chat 33 upvotes 2 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community Diffuse thinning is so brutal.

in Styling 72 upvotes 1 year ago

A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

community Actor Jacob Batalon, 26, has a receding hairline. I thought it was pretty cool to see a younger actor being successful, despite dealing with hair loss. His most well known role is Ned Leeds in the Marvel Cinematic Universe, and he is currently the CEO of Sex.

in Satire 498 upvotes 1 year ago

Actor Jacob Batalon's receding hairline and how it is a sign of his success despite dealing with hair loss, with some people suggesting he may be using treatments such as Minoxidil or Finasteride to manage it.

community So we’re just ok with taking a research chemical now?

in Treatment 179 upvotes 3 years ago

The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

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