New Therapeutic Aspects In Non-Cicatricial Alopecias

    August 1988 in “ PubMed
    H Zaun
    TLDR New treatments for hair loss show promise, especially with antiandrogens, minoxidil, and autoimmune therapies.
    The document reviewed new therapeutic approaches for non-cicatricial alopecias as of 1988. It highlighted promising results from pharmacological and clinical studies, including the development of effective antiandrogens for topical use in treating androgenetic alopecia in men. It also noted that further research on minoxidil could enhance understanding of follicular function regulation. Additionally, preliminary experiences with various treatments for alopecia areata, based on its autoimmune nature, were seen as foundational for developing effective practical therapeutic regimens.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  121 upvotes 2 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

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