TLDR Proteomics helps understand protein changes in wool fiber development.
This study aimed to explore the potential of proteomics to shed light on protein changes during the stages of protein synthesis and keratinisation in maturing wool fibers. Previous research indicated a sequential pattern of expression for major keratin and keratin-associated proteins in hair follicles of both sheep and humans. However, the relationship between expression sequence, post-translational changes, and fiber development was not well understood. The study sought to address this gap by using proteomics to gain insights into these processes.
95 citations
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March 2009 in “Differentiation” Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.
276 citations
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January 2005 in “International review of cytology” 252 citations
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January 1991 in “Electron Microscopy Reviews”
50 citations
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July 2008 in “British Journal of Dermatology” 138 citations
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March 2007 in “Experimental cell research” Only a few hair-specific keratins are linked to inherited hair disorders.
276 citations
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January 2005 in “International review of cytology” 199 citations
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January 2004 in “The International Journal of Developmental Biology” Hair follicle growth and development are controlled by specific genes and molecular signals.
29 citations
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April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
