The oestrogen receptor 2 (ESR2) gene in female-pattern hair loss: replication of association with rs10137185 in German patients
April 2014
in “British Journal of Dermatology”
TLDR ESR2 gene linked to female-pattern hair loss.
The study aimed to replicate the association between the ESR2 gene and female-pattern hair loss (FPHL) found in an Australian sample. The researchers investigated three variants in the ESR2 gene in a German/U.K. FPHL case-control sample and found significant association for rs10137185 in the overall sample. The study supports the previous finding that the ESR2 gene is associated with FPHL.
View this study on academic.oup.com →
Cited in this study
research Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss
AR/EDA2R gene linked to early-onset female hair loss, but 20p11 gene not involved.
research Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified
No link found between specific genes and female pattern hair loss.
research Association analysis of oestrogen receptor beta gene ( ESR2 ) polymorphisms with female pattern hair loss
ESR2 gene variations may be linked to female pattern hair loss.
research Investigation of variants of the aromatase gene (CYP19A1) in female pattern hair loss
No link found between aromatase gene and female hair loss.
research The reliability of horizontally sectioned scalp biopsies in the diagnosis of chronic diffuse telogen hair loss in women
Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.
research Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex
Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.