The efficacy of scalp cooling in patients receiving chemotherapy for primary gynecologic cancers: a randomized controlled trial

March 2026 in “ Scientific Reports ”

Shuk Tak Kwok, Lesley Suk Kwan Lau, Tat On Chan, Mandy Man Yee Chu, Siew Fei Ngu, Karen Kar Loen Chan, Hextan Yuen Sheung Ngan, Pei Ho, Lina Wu, Damaris Suk Mei Hung, H. P. Lo, Christina Sze Man Wong, Ka Yu Tse

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Research cited in this study

8 / 8 results

research Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?

4 citations , March 2023 in “Current Oncology”

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

research Efficacy of Acupuncture and Moxibustion in Alopecia: A Narrative Review

June 2022 in “Frontiers in Medicine”

Acupuncture and moxibustion may help treat hair loss, but more research is needed.

research Hair Disorders in Patients with Cancer

53 citations , April 2018 in “Journal of The American Academy of Dermatology”

Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.

research Management of Chemotherapy-Induced Alopecia With Scalp Cooling

25 citations , March 2018 in “Journal of oncology practice”

Scalp cooling is an effective and safe way to prevent hair loss from chemotherapy, with manageable side effects and low risk of scalp cancer.

research Pathogenesis and Treatment Options for Chemotherapy-Induced Alopecia: A Systematic Review

34 citations , January 2018 in “International Journal of Dermatology”

Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.

research Scalp Hypothermia as a Preventative Measure for Chemotherapy-Induced Alopecia: A Review of Controlled Clinical Trials

37 citations , October 2017 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Scalp cooling effectively reduces hair loss from chemotherapy.

research Cold Thermal Injury from Cold Caps Used for the Prevention of Chemotherapy-Induced Alopecia

22 citations , May 2016 in “Breast cancer research and treatment”

Some patients using cold caps to prevent hair loss from chemotherapy got mild scalp injuries similar to frostbite.

research Simulation of Scalp Cooling by External Devices for Prevention of Chemotherapy-Induced Alopecia

7 citations , December 2015 in “Journal of thermal biology”

Scalp cooling devices need to be powerful enough to overcome heat loss and reach the right temperature to prevent hair loss from chemotherapy.