Effect of Tannin on Gene Expression Related to Hair Cycle in Skin Tissue of Mice with DNCB-Induced Dermatitis

June 2019 in “ 대한미용학회지 ”

장경화, 류은미

tannin 2,4-dinitrochlorobenzene contact dermatitis hair follicles gene expression dermatitis symptoms

TLDR Tannin improved dermatitis symptoms and may help hair growth in affected mice.

The study investigated the effects of tannin on hair growth in mice with contact dermatitis induced by 2,4-dinitrochlorobenzene (DNCB). Mice treated with tannin showed significant improvement in dermatitis symptoms such as skin rash and scab formation compared to untreated mice. Histological analysis revealed clearer boundaries between skin layers and hair follicles in tannin-treated mice. Additionally, the expression of several hair-related genes was increased in the tannin-treated group. The study concluded that tannin improved dermatitis symptoms and may aid in overcoming hair growth impediments caused by dermatitis.

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