Hair Safe Study: Effects of Scalp Cooling on Hair Preservation and Hair Regrowth in Breast Cancer Patients Receiving Chemotherapy - A Prospective Interventional Study

April 2022 in “ The Breast ”

Christine Brunner, Miriam Emmelheinz, R Kofler, Samira Abdel Azim, Marlene Lehmann, Verena Wieser, Magdalena Ritter, Anne Oberguggenberger, Christian Marth, Daniel Egle

scalp cooling chemotherapy-induced alopecia taxane monotherapy

TLDR Scalp cooling reduces hair loss during chemotherapy but doesn't help hair regrow after.

The study examined the effects of scalp cooling on hair preservation and regrowth in breast cancer patients undergoing chemotherapy. It involved 128 patients and found that scalp cooling significantly reduced chemotherapy-induced alopecia, with 24% of patients experiencing less than 50% hair loss, compared to 0% in the control group. Scalp cooling was particularly effective for patients receiving taxane monotherapy. However, it did not significantly impact hair regrowth post-chemotherapy, and patient self-assessments were more critical than expert evaluations. The study noted high discontinuation rates due to adverse effects like scalp pain and cold sensation, and highlighted the importance of patient involvement in outcome reporting. Despite its efficacy in hair preservation, scalp cooling did not enhance hair regrowth or quality of life.

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Research cited in this study

3 / 3 results

research The Influence of Various Parameters on the Success of Sensor-Controlled Scalp Cooling in Preventing Chemotherapy-Induced Alopecia

21 citations , January 2015 in “Oncology Research and Treatment”

Scalp cooling can prevent hair loss in 65% of chemotherapy patients, especially effective in breast cancer patients and certain chemotherapy types.

research Efficacy and Tolerability of Two Scalp Cooling Systems for the Prevention of Alopecia Associated with Docetaxel Treatment

52 citations , May 2013 in “Supportive Care in Cancer”

Scalp cooling significantly reduces hair loss in chemotherapy patients.

research Chemotherapy-Induced Alopecia

103 citations , December 2011 in “Journal of the American Academy of Dermatology”

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

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