Safety Profile of Topical Spray Minoxidil: An Observational Study

January 2025

Lina Benchekroun, Lina Mouline, Hanane Darghal, Mariame Meziane, N. Ismaïli, Laïla Benzekri

topical minoxidil androgenetic alopecia telogen effluvium scalp irritation facial hypertrichosis dandruff Rogaine

Studysummary This study reported that 72% of topical minoxidil users experienced adverse effects, such as scalp irritation and facial hypertrichosis, although only 20% discontinued treatment, indicating that longer use may improve tolerance despite initial side effects.

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research Compliance to Topical Minoxidil and Reasons for Discontinuation Among Patients With Androgenetic Alopecia

April 2023 in “Dermatology and therapy”

This study found a high discontinuation rate of topical minoxidil among patients with androgenetic alopecia, largely influenced by short treatment duration, lack of efficacy, and adverse effects.

research Effectiveness of the Active Ingredients (Capixyl, Procapil, and Rosemary Extract) of the Trust Tonic for the Treatment of Androgenetic Alopecia in Comparison to Minoxidil

October 2022 in “Our Dermatology Online”

In this study, researchers compared the effectiveness of a tonic containing Capixyl, Procapil, and rosemary extract with 2% minoxidil in reducing hair loss and promoting hair growth in male participants over a 24-week period.

research Microneedling for Androgenetic Alopecia Not Responding to Conventional Treatment

3 citations , March 2020 in “Our Dermatology Online”

In this case series from Nepal, microneedling in combination with oral finasteride and minoxidil was associated with moderate to significant hair growth improvement in androgenetic alopecia patients, with high satisfaction and no complications reported.

research Safety of Topical Minoxidil Solution: A One-Year, Prospective, Observational Study

26 citations , July 2003 in “Journal of Cutaneous Medicine and Surgery”

This study found that topical minoxidil solution is a safe treatment for androgenetic alopecia, with no increase in cardiovascular events or adverse pregnancy outcomes observed.